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+ servings
pepperoni pizza bread topped with mozzarella cheese
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5 from 5 votes

Pepperoni Bread

Pepperoni Bread is made from scratch with mozzarella, parmesan, oregano, and lots of diced pepperoni. A stand mixer does most of the kneading for you! The perfect dinner bread that's crusty on the outside and moist and soft on the inside. This is the best pepperoni pizza bread you'll ever have!
Prep Time1 hr 30 mins
Cook Time45 mins
Total Time2 hrs 15 mins
Course: Appetizer
Cuisine: American
Keyword: bread from scratch, dinner bread, game day party food
Servings: 16 slices
Calories: 135kcal
Author: Kristina


  • 1 cup water
  • ¼ cup plain yogurt
  • 2 ½ cups bread flour
  • 1 ½ tsp salt
  • 2 tbsp sugar
  • 1 tsp oregano
  • 2 ¼ tsp instant yeast
  • ¼ cup parmesan cheese (plus more for sprinkling)
  • 1 ¼ cup shredded mozzarella (divided)
  • ½ cup pepperoni, diced


  • In a saucepan, heat water and yogurt until steaming, stirring occasionally. Remove from the heat and let cool for 5 minutes.
  • While the yogurt cools, combine flour, salt, sugar, yeast, oregano, and parmesan cheese in the bowl of a stand mixer. Add the yogurt mixture ,1 cup of mozzarella and pepperoni. Mix on low speed 2 for 5 minutes.
  • Remove dough and transfer to an oiled baking sheet. Shape into a ball, cover with a heavy cloth, and set in a warm place to rise for 1 hour. (hint: warm the oven for a few minutes, turn off, and let the bread rise in the closed oven)
  • Knead the dough a few more times and shape into a ball or rectangle. Slice an "X" in the top, cover with a cloth, and let rise for 10 minutes. Preheat the oven to 350°.
  • Bake for 30 minutes. Brush the top lightly with oil and sprinkle with remaining ¼ cup of mozzarella and parmesan. Bake for another 15 minutes.
  • Remove from the oven, transfer to a wire rack to cool for 15 minutes before slicing.


  • You can use plain regular yogurt in place of Greek. I've used both and the only difference is that the bread made with Greek yogurt is a little more moist and chewy.
  • If using fresh oregano instead of dried, make sure to use triple the amount. 
  • You can use specialty pepperoni or pre-sliced packaged pepperoni. Specialty will be chunkier in the bread, while packaged pepperoni will be smaller and softer. 


Serving: 1slice | Calories: 135kcal | Carbohydrates: 17g | Protein: 7g | Fat: 5g | Saturated Fat: 2g | Cholesterol: 12mg | Sodium: 363mg | Potassium: 58mg | Fiber: 1g | Sugar: 2g | Vitamin A: 76IU | Calcium: 72mg | Iron: 1mg